VetIOS publishes CIRE as a versioned standard so partners, researchers, and regulators can reason about inference confidence, safety state, and outcome-linked lineage without depending on a private UI.
Inference certainty entropy score
phi_hat = 1 - H(D) / ln(|D|), where H(D) = -sum(p_i * ln(p_i)) over normalized differential probabilities
Higher values mean the differential distribution is more concentrated and easier to act on.
Input quality risk score
input_m_hat = 0.40 * missingness + 0.35 * contradiction_rate + 0.25 * out_of_distribution_rate
Higher values mean the clinical input is incomplete, contradictory, or outside the supported operating envelope.
Rolling reliability drift
delta_rolling = EMA(delta_hat, alpha = 0.1)
Tracks short-horizon movement in reliability compared with prior inference behavior.
Reliability volatility
sigma_delta = standard_deviation(last 50 delta_hat values)
Higher values indicate less stable reliability behavior across recent events.
Clinical perturbation score
cps = 0.40 * (1 - phi_hat / phi0) + 0.35 * max(0, -delta_rolling) / phi0 + 0.25 * sigma_delta / phi0
Composite safety score used to decide whether an inference is high confidence, reviewable, cautionary, or suppressed.
The inference is within the expected reliability envelope.
Show the differential with normal clinical decision-support language.
The inference should be interpreted with clinician review because reliability has weakened.
Surface uncertainty and recommend additional diagnostic confirmation.
The inference is unstable enough to require explicit caution.
Show the result as decision support only and avoid workflow automation.
The inference is outside the safe publication envelope.
Suppress the clinical answer and require human review or better input.
The standard is public; the managed VetIOS infrastructure remains the commercial product. Partners can cite the reliability contract, while production deployments use VetIOS for hosted inference, outcome lineage, model cards, network learning, and enterprise/government API access.