evidence-aware intelligence infrastructure

Connect intelligence to verified outcomes.

VetIOS connects clinical evidence, reasoning, verification, and observed outcomes in an auditable workflow. A versioned inference engine and CIRE publication gates make the reasoning inspectable; later evidence tests the original decision.

VetIOS was founded in Nairobi, Kenya. Veterinary medicine is the first proving ground for a broader biological intelligence infrastructure vision.

clinical showcasesynthetic caseveterinary review pending

Five-month-old incompletely vaccinated puppy with hemorrhagic diarrhea

A synthetic five-month-old mixed-breed puppy with an incomplete vaccination series develops acute lethargy and anorexia, followed within a day by repeated vomiting and hemorrhagic diarrhea. It is moderately dehydrated. The CBC shows leukopenia with neutropenia.

engine differential, before any confirmatory test

Reported probabilities for the top named conditions. Mass the engine assigns elsewhere is shown as the residual, never redistributed.

Parvoviral Enteritis13.7%
Infectious Colitis10.8%
Dietary Enterocolitis10.3%
Clostridial Enterotoxicosis9.5%
Acute Hemorrhagic Diarrhea Syndrome8.3%
Residual (other conditions)47.5%
Evidence for Parvoviral Enteritis: Neutropenia on CBC: characteristic of parvoviral enteritis; Presenting sign: vomiting; Presenting sign: diarrhea; Presenting sign: bloody diarrhea; Presenting sign: dehydration; Presenting sign: lethargy. Against: none reported.
CIRE decision
Publication
REVIEW
Structural
REVIEW
Clinical reliability
UNVALIDATED
Differential concentration
0.1464
verified outcome (synthetic truth fixture)

fecal canine parvovirus antigen (ELISA): positive. Confirmed: Canine parvoviral enteritis.

The engine ranked it first before the test. CI regenerates this case and fails if that changes.

reasons: Structural risk → REVIEW

limitations generated from this run
  • The pre-test differential is flat: the leading condition holds 13.7% of the reported mass, so CIRE publishes REVIEW.
  • Clinical expectation places Acute Hemorrhagic Diarrhea Syndrome in the top three; the engine ranks it 5th.
  • Known condition-registry normalization issue: 5 conditions are registered under more than one identifier (Acute Pancreatitis, Gastric Dilatation-Volvulus, Hypoadrenocorticism, Immune-Mediated Thrombocytopenia, Leptospirosis). Normalization is pending.
  • Acute hemorrhagic diarrhea syndrome remains a differential. It is classically accompanied by hemoconcentration (PCV often above 60%); anemia is not expected. No PCV is supplied, and low PCV is never used as AHDS evidence.
  • A positive fecal antigen is treated by the engine as confirmatory. False positives shortly after modified-live parvovirus vaccination are not modeled.

The engine output for this synthetic case has not yet been reviewed by a veterinarian.

engine clinical_deterministic_multisystem_v1 · semantics categorical_topk_with_other · evaluated 2026-09-26 · regenerated from the engine and compared in CI

How CIRE decides
architecture

A decision that can be traced to its outcome.

Typed evidence, explicit reasoning, verification, and outcome-linked evaluation form one auditable workflow.

01
Structured case intake

Cases enter as typed clinical input: species, signalment, presenting signs, history, and structured diagnostic tests.

Typed case evidence

02
Inference kernel

A versioned rules engine ranks conditions and lists the supporting and contradicting evidence for each one.

Versioned reasoning

03
CIRE publication gate

CIRE checks probability semantics and structure, then publishes NOMINAL, REVIEW, CAUTION, or SUPPRESSED before anything is actionable.

Explicit publication decision

04
Outcome receipt

Later observations are linked to the original inference, preserving the prediction, confirmed outcome, and evidence provenance.

Decision-to-outcome lineage

05
Evaluation factory

Eligible outcome-grounded cases become replayable evaluations and regression evidence for reviewing a candidate release.

Reusable evaluation evidence

Explore the platform and its verification principles.

decision to outcome

Clinical work becomes reusable evidence.

For clinical teams, laboratories, and AI evaluators, the useful record connects a decision to the observations that test it.

Reason through a clinical case

Bring history, observations, and diagnostic findings into a structured case. Inspect hypotheses alongside their supporting evidence, contradictions, and uncertainty.

A recorded inference with its evidence trail.

Connect what happened next

Link confirmatory tests and reviewed outcomes to the original prediction. Preserve the earlier reasoning so later evidence can confirm, revise, or falsify it.

An outcome receipt with provenance and case lineage.

Evaluate the next change

Replay eligible cases against a candidate model, policy, or workflow. Compare results before promotion and retain the evidence behind each release decision.

An executable evaluation and a reviewable release gate.

Follow a reproducible example in ProofLoop. Demonstration fixtures are identified separately from clinical outcome evidence.

operator media

A field note inside the control plane.

The video is context, not the product. VetIOS should feel like the clinical data substrate underneath every visible interface: provenance-aware, outcome-linked, and operational before it is theatrical.

source
field signal
embed
click-to-load
autoplay
off
fallback
youtube link
media trace
::media.source accepted youtube:kE5jfdzfwak
::embed.mode click_to_load
::privacy.mode youtube_nocookie
::fallback.ready external_link
field signal
source
substrate
provenance first
position
supporting evidence
surface
no autoplay
developer infrastructure

API-first, typed, and observable.

Every example below is generated from the canonical partner contract and validated against the runtime request schemas in CI.

One external contract at https://www.vetios.tech/api/v1, authenticated with a Bearer vios_k1_ partner key. These cards, the OpenAPI specification, and the SDK are generated from the same contract.

POST/api/v1/inference/differential
typed route
// curl integration
curl -X POST https://www.vetios.tech/api/v1/inference/differential \
  -H "Authorization: Bearer $VETIOS_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"species":"canine","breed":"mixed breed","age_years":0.42,"weight_kg":6.2,"sex":"male_intact","region":"Nairobi","presenting_signs":["lethargy","anorexia","vomiting","bloody diarrhea","dehydration"],"history":{"duration_days":2,"progression":"acute","owner_observations":["Lethargy and anorexia began first","Repeated vomiting and hemorrhagic diarrhea followed within a day"]},"preventive_history":{"vaccination_status":"incomplete","deworming_history":"unknown"},"diagnostic_tests":{"cbc":{"leukopenia":"present","neutropenia":"present"}}}'
// request
{
  "species": "canine",
  "breed": "mixed breed",
  "age_years": 0.42,
  "weight_kg": 6.2,
  "sex": "male_intact",
  "region": "Nairobi",
  "presenting_signs": [
    "lethargy",
    "anorexia",
    "vomiting",
    "bloody diarrhea",
    "dehydration"
  ],
  "history": {
    "duration_days": 2,
    "progression": "acute",
    "owner_observations": [
      "Lethargy and anorexia began first",
      "Repeated vomiting and hemorrhagic diarrhea followed within a day"
    ]
  },
  "preventive_history": {
    "vaccination_status": "incomplete",
    "deworming_history": "unknown"
  },
  "diagnostic_tests": {
    "cbc": {
      "leukopenia": "present",
      "neutropenia": "present"
    }
  }
}
// response
DifferentialDiagnosisResponse {
  inference_event_id: string | null
  clinical_case_id: string | null
  data: object
  output_payload: InferenceOutputPayload
  global_condition_expansion?: object
  latency_ms: number
  cire: CireSignals
  clinical_actionability: ClinicalActionability
  actionability_gate?: object | null
  formal_constraint_ledger: object
  ranker: string
}
POST/api/v1/outcomes/contribute
typed route
// curl integration
curl -X POST https://www.vetios.tech/api/v1/outcomes/contribute \
  -H "Authorization: Bearer $VETIOS_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"request_id":"33333333-3333-4333-8333-333333333333","inference_event_id":"11111111-1111-4111-8111-111111111111","outcome":{"type":"diagnosis_confirmed","payload":{"label":"Canine parvoviral enteritis","confidence":0.99,"label_type":"lab_confirmed","reviewer_exposure":"unknown","verification_context":{"schema_version":"outcome-verification-context-v1","testing":{"decision":"performed","reason":"Diagnostic verification requested at presentation."},"reference_standard":{"name":"Laboratory report","evidence_refs":["44444444-4444-4444-8444-444444444444"]},"specimen_timing":"unknown"},"lab_result_id":"44444444-4444-4444-8444-444444444444"},"timestamp":"2026-06-06T12:00:00.000Z"}}'
// request
{
  "request_id": "33333333-3333-4333-8333-333333333333",
  "inference_event_id": "11111111-1111-4111-8111-111111111111",
  "outcome": {
    "type": "diagnosis_confirmed",
    "payload": {
      "label": "Canine parvoviral enteritis",
      "confidence": 0.99,
      "label_type": "lab_confirmed",
      "reviewer_exposure": "unknown",
      "verification_context": {
        "schema_version": "outcome-verification-context-v1",
        "testing": {
          "decision": "performed",
          "reason": "Diagnostic verification requested at presentation."
        },
        "reference_standard": {
          "name": "Laboratory report",
          "evidence_refs": [
            "44444444-4444-4444-8444-444444444444"
          ]
        },
        "specimen_timing": "unknown"
      },
      "lab_result_id": "44444444-4444-4444-8444-444444444444"
    },
    "timestamp": "2026-06-06T12:00:00.000Z"
  }
}
// response
OutcomeContributionResponse {
  outcome_event_id: string | null
  clinical_case_id: string | null
  linked_inference_event_id: string | null
  calibration_delta: number | null
  prediction_correct: boolean | null
  deprecated_fields?: object
  diagnosis_record_id?: string | null
  derived_updates: object
  request_id: string
  meta?: object
  error?: string | null
}
GET/api/v1/models/card
typed route
// curl integration
curl -X GET https://www.vetios.tech/api/v1/models/card \
  -H "Authorization: Bearer $VETIOS_API_KEY"
// request
(no request body)
// response
ModelCardResponse {
  tenant_id: string
  refreshed_at: string
  cards: ModelCard[]
}
infrastructure primitives

Evidence that survives a change of model.

Cases, policies, outcomes, and evaluations carry their own provenance across the intelligence workflow.

module
Typed evidence

Structured observations with their source and clinical context

module
Versioned reasoning

Recorded predictions tied to engine and policy versions

module
Verification policy

Publication gates, explicit uncertainty, and escalation

module
Outcome provenance

Later evidence linked to the decision it evaluates

module
Replayable evaluations

Case-based checks before a candidate is promoted

module
Tenant governance

Scoped access and consent for evidence reuse

work with us

Build a workflow whose outcomes can be verified.

Work with VetIOS on clinical reasoning, laboratory reconciliation, outcome feedback, or AI evaluation. Define the decision, the evidence it needs, and the observation that will verify the result.

DESIGN PARTNERSHIPS AND PILOTS: partnerships@vetios.tech · RESEARCH AND VALIDATION: research@vetios.tech